TCM China:  

Record of Herbal Treatment Of Thanasis from Greece Improvement Of ALS
 

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Brief Summary: An ALS patient, Thanasis, from Greece, who suffered from difficulties in speaking and swallowing and the weakness of his left fingers, was hospitalized in our hospital. He has achieved significant improvement after more than two-month TCM treatment in our hospital, especially his improvement in swallowing and speaking.

 

Record of Hospitalization

Name: Thanasis                                                                                                            Sex: Male

Age: 57                                                                                                                          Profession:  Office Clerk

Nationality: Greece                                                                                                       Marital Status: Married

Onset Season: Summer                                                                                                  Date of Admission: July 21, 2007  

Complainer: The patient himself                                                                                    Reliability: Reliable

Major Complaint: The patient has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months.

Present Illness: In July 2005, the patient began to feel unclearness and disfluency of his speaking with some difficulty in swallowing without any obvious causes. He coughed when he drank water. But at that time, the patient paid no attention to it, and did no treatment about it. Therefore, the disease was developing progressively. In Oct. 2006, the patient began to feel weakness of his left fingers, and then went to a local hospital for a diagnosis. After the EMG examination, the patient was diagnosed with amyotrophic lateral sclerosis (ALS). The patient was told that his disease was incurable, and then he got no treatment. In Feb. 2007, the patient went to another local hospital for a further diagnosis, and he was prescribed by some western medicine for oral taking until now. He was picked up by our staff in Zhijiang Airport and arrived in Huaihua Red Cross Hospital for further treatment at 19: 00 p.m. on July 21, 2007. Since he got the disease, his sleep and appetite were both poor. His spirit was good. His bowel movement and urination were both normal. 

Disease History: No history of typhoid, tuberculosis, hepatitis, malaria or other infectious diseases. No allergic history of medicine or food. No trauma history. No history of preventive vaccination provided. In 1997, he got an operation for his hernia. But now, it is cured. In 1997, he suffered from diabetes. Since then, he has taken the medicine for it until now.

 Personal History: He was born in Greece. No contact history of schistosomiasis. No addiction to smoking, alcohol or special food. He was mild-tempered and open-minded.

Marital History: He got married at the age of 29. He has one son. His wife and child have been healthy all the time.

Family History: His parents were both healthy. No family history of special disease.

Physical Examination:

T 36.5¡æ£¬P 80 beats/minute, R 18 times/minute, BP 130/85 mmHg, W 98 kg.

He grew normally with common nourishment. His mind was clear. He had an expression of chronic illness and languidness. His body was in a positive posture and he was cooperative in examination. His skin was moist. No jaundice in the sclera. No superficial lymph-node enlargement. Bilateral pupils were round and equal in size and sensitive to light. No thoracic deformity. Sound of breath was bilaterally normal on auscultation. No respiratory rales or pleural friction rubs. Heart border was normal. Heart beat was 80 times/minute. Cardiac rhythm was regular. No pathological murmurs on auscultation. Abdomen touched flat and soft without tenderness or rebounding tenderness. The liver and spleen were not palpable. No percussion pains in renal region. Bowel sound was normal. No spinal and pelvic deformity or tenderness. He suffered from unclearness and disfluency of speech, accompanied by difficulty in swallowing, poor movement of his tongue and coughing as drinking. His tongue was rugged with atrophic tongue muscles. His fingers were suffered from weakness so that he had difficulty in holding any objects. The muscles of his hands were atrophic. The experiment on his hands was (+). There was uncontrollable and frequent muscles¡¯ trembling on his upper limbs, chest and back. The muscle strength of his upper limbs was Grade ¢ó with low muscle hypertonicity. His lower limbs were weak in free movement without any tenderness or deformity. The examinations of the anus and pudendum were both normal. Other physiological reflex has not been elicited. His tongue was red with white and slightly heavy-greasy tongue coating. His pulse was slippery, thready and weak.

Diagnostic examination: Not provided.

First Diagnosis: 

TCM diagnosis: Wilting syndrome

Symptom identification: Spleen-kidneys lungs vacuity.

Western medicine diagnosis: Amyotrophic Lateral Sclerosis (ALS)

 

First Medical Record

July 18, 2007 

Thanasis, a 57-year-old male, has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months. He was picked up by our staff in Zhijiang Airport and arrived in Huaihua Red Cross Hospital for further treatment at 19: 00 p.m. on July 21, 2007.

Essentials for Diagnosis:

1. The patient has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months.

2. In July 2005, the patient began to feel unclearness and disfluency of his speech with some difficulties in swallowing without any obvious causes. He coughed when he drank water. But at that time, the patient paid no attention to it, and did no treatment about it. Therefore, the disease was developing progressively. In Oct. 2006, the patient began to feel weakness of his left fingers, and then went to a local hospital for a diagnosis. After the EMG examination, the patient was diagnosed with amyotrophic lateral sclerosis (ALS). The patient was told that his disease was incurable, and then he got no treatment. In Feb. 2007, the patient went to another local hospital for a further diagnosis, and he was prescribed by some western medicine for oral taking until now. He was picked up by our staff in Zhijiang Airport and arrived in Huaihua Red Cross Hospital for further treatment at 19: 00 p.m. on July 21, 2007. Since he got the disease, his sleep and appetite were both poor. His spirit was good. His bowel movement and urination were both normal. 

3. T 36.5¡æ£¬P 80 beats/minute, R 18 times/minute, BP 130/85 mmHg, W 98 kg.

4. He grew normally with common nourishment. His mind was clear. He had an expression of chronic illness and languidness. His body was in a positive posture and he was cooperative in examination.

5. He suffered from unclearness and disfluency of speech, accompanied by difficulty in swallowing, poor movement of his tongue and coughing as drinking. His tongue was rugged with atrophic tongue muscles. His fingers were suffered from weakness so that he had difficulty in holding any object. The muscles of his hands were atrophic. The experiment on his hands was (+). There was uncontrollable and frequent muscles¡¯ trembling on his upper limbs, chest and back. The muscle strength of his upper limbs was Grade ¢ó with low muscle hypertonicity. His lower limbs were weak in free movement without any tenderness or deformity. The examinations of the anus and pudendum were both normal. Other physiological reflex has not been elicited. His tongue was red with white and slightly heavy-greasy tongue coating. His pulse was slippery, thready and weak.

6. No thoracic deformity. Chest percussion noted resonance. Sound of breath is bilaterally clear on auscultation. No sound of pleural friction.

7. Diagnostic examination: Not provided

Diagnostic Basis:

TCM: The patient has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months. The muscles of his upper limbs were atrophic and weak, accompanied with languid spirit and pale faces. His speech was neither clear nor frequent, with difficulty in swallowing, poor movement of his tongue and coughing as drinking. His tongue was rugged with atrophic tongue muscles. His tongue was red with white and slightly heavy-greasy tongue coating. His pulse was slippery, thready and weak. Because of the insufficiency of the liquids, abnormality of the qi and blood, and the lungs heat scoring the lobes, his limbs lose the nutrition. Due to the deficiency of the spleen and stomach, the essence-blood could not nourish his sinews and vessels. Then it leads to the malnutrition of the muscles, and gradually it resulted in flaccidity.

Western Medicine: The patient has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months. He suffered from unclearness and disfluency of speech, accompanied by difficulty in swallowing, poor movement of his tongue and coughing as drinking. His tongue was rugged with the atrophic tongue muscles. His fingers were suffered from weakness so that he had difficulty in holding any object. The muscles of his hands were atrophic. The experiment on his hands was (+). There was uncontrollable and frequent muscles¡¯ trembling on his upper limbs, chest and back. The muscle strength of his upper limbs was Grade ¢ó with low muscle hypertonicity. In Oct. 2006, after the EMG examination, he was diagnosed with amyotrophic lateral sclerosis (ALS).

Diagnostic Differentiation:

TCM: The patient¡¯s wilting syndrome should be differentiated from impediment syndrome. Wilting syndrome is characterized by the limp, weak, and emaciated limbs with muscular atrophy. A patient suffered from wilting syndrome may even become unable to hold any objects or to stand without any support. Besides, the patient¡¯s lower limbs are more often affected, though he or she usually has no joint pains. On the contrary, impediment syndrome is generally characterized by aching pains, fixed heaviness and inflexibility of sinews and bones, muscles and joints, with occasional numbness or swelling, though, no paralytic manifestations. They are not difficult to be distinguished in clinics.

Western Medicine: Wilting syndrome should be differentiated from grave myasthenia gravis, which is an acquired autoimmune disease with the transferring obstacles of nerve-muscles, and is caused by the autoimmune reaction resulting from the acetylcholine receptor (AchR) of the striated muscle. It can occur at any age and there are about 60 percent people stricken before 30 years old. Women are more often affected than men are. The most obvious characteristic of MG is rapid fatigability of the skeletal muscles affected, improved with rest or medicines that inhibits the activity of cholinesterase. It can involve the cardiac muscle and smooth muscle. MG patients of different ages often have different clinical manifestations and courses, which are different from those of wilting syndrome patients.

First Diagnosis: 

TCM diagnosis: Wilting syndrome

Symptom identification: Spleen-kidneys lungs vacuity

Western medicine diagnosis: Amyotrophic Lateral Sclerosis (ALS)

Plans for treatment strategy and nursing:

1. Routine care of traditional Chinese internal medicine.

2. Grade II care.

3. Under the care of a companion.

4. High-protein diet.

5. Herbal tea (to boost qi and fortify the spleen, supplement the kidneys and boost the lungs): Taking five dosages of the herbal tea. One dosage a day and drink twice.

Prescription: Varied Decoction of the Fortifying-Spleen and Supplementing-Kidneys.

Main herbs used in the herbal tea: baisheng (white ginseng), huangqi (astragalus root), baishu (ovate atractylodes root), etc.

6. Acupuncture and massage: Once a day.

7. Take more exercise on the tongue and the suffering parts.

8. Have more medical examinations if necessary.

 

Date: July 22, 2007                               Time: 10:00 a.m.

The patient has suffered from difficulties in speaking and swallowing for two years, accompanied with weakness of his left fingers for nine months. The patient began to suffer from unclearness speech, accompanied with difficulty in swallowing, coughing as drinking two years ago, and his condition was getting worse day by day. Nine months ago, he began to feel the weakness of his left fingers with difficulty in holding any objects. His finger and arms were both suffered from muscular atrophy, and muscular trembling of the upper body. His food intake was poor. Sometimes he felt there was some phlegm on his throat. His lower limbs were weak. His tongue coating was slightly heavy-greasy with rugged lingual surface. The muscles of his tongue were atrophic and trembling. There were tooth-marks at the edges of the tongue. The movement of his tongue was poor. His pulse was slippery, thready and weak.

TCM diagnosis: Wilting syndrome

Symptom identification: Spleen-kidneys lungs vacuity.

Western medicine diagnosis: Amyotrophic Lateral Sclerosis (ALS)

Principle of TCM treatment: Boosting qi and fortifying the spleen, supplementing the kidneys and boosting the lungs.

Doctor¡¯s requirement is to take four dosages of the herbal tea of the same prescription.

 

Date: July 25, 2007                               Time: 10:00 a.m.

The patient felt that his difficulty in swallowing got some improvement. Doctor¡¯s requirement is that he would continue to take five dosages of the herbal tea of the former prescription.

 

Date: July 30, 2007                               Time: 9:00 a.m.

His swallowing and movement of his tongue was getting better. His sleep was bad with nightmare. The doctor advised him to add poria, spiny jujube kernel and polygala root decocted into the former prescription.

 

Date: July 31, 2007                               Time: 9:00 a.m.

Today the patient complained that his swallowing, the movement of his tongue and the muscular fibrillation all over his body all achieved some improvement. His sleep was still poor, while his diet was normal. The TCM strategy was to boost qi and fortify the spleen, supplement the kidneys and boost the lungs, soften the liver and extinguish the wind. He would continue to take four dosages of the herbal tea of the former prescription.

 

Date: Aug. 2, 2007                               Time: 9:00 a.m.

His fingers of both hands were weak with difficulty in flexible movement of joints. The doctor advised him to take four dosages of the herbal tea to soak his hands. The main herbs in the herbal tea for external use are cinnamon twig, ground pine, millettia root and stem, etc.

 

Date: Aug. 4, 2007                               Time: 9:00 a.m.

Today the patient complained that his swallowing, the movement of his tongue and the muscular fibrillation all over his body all achieved some improvement. His sleep was better than before. Sometimes he felt some pains on his arms. Doctor¡¯s requirement is to take five dosages of the herbal tea of the same formula.

 

Date: Aug. 9, 2007                               Time: 9:00 a.m.

The muscular fibrillation all over his body was lessened. He spoke very slowly with dry month and inflexible movement of his tongue. His lingual surface was tugged with its muscular atrophy. His tongue coating was white with less liquid. The TCM strategy was to boost qi and fortify the spleen, supplement the kidneys and boost the lungs, and extinguish the wind. He would continue to take five dosages of the herbal tea of the former prescription.

 

Date: Aug. 11, 2007                               Time: 9:00 a.m.

His fingers of the hands were with muscular atrophy and poor movement of the fingers. The oral taking herbal tea should combine with five dosages of the herbal tea for the external use. The main herbs in the herbal tea for external use are cinnamon twig, ground pine, millettia root and stem, etc.

 

Date: Aug. 14, 2007                               Time: 9:30 a.m.

The patient¡¯s difficulty in swallowing and the muscular fibrillation all over his body both achieved obvious improvement. His difficulty in speaking was also getting better. The strength of the limbs increased. He could raise his thumb to praise something good. He also complained that he felt dumbness of his fingers and dryness of his mouth at night, sometimes accompanied with a drumming in the ears. Doctor¡¯s requirement is to take five dosages of the herbal tea of the same prescription.

 

Date: Aug. 19, 2007                               Time: 9:00 a.m.

The patient¡¯s diet was poor, but his dry month was getting better. His tongue coating was slightly greasy. He would continue to take five dosages of the herbal tea of the same prescription, adding tangerine peel into it.

 

Date: Aug. 24, 2007                               Time: 9:00 a.m.

The patient complained that his difficulties in speaking and swallowing achieved significant improvement. The upper limbs were painful, and his diet was poor. Doctor¡¯s requirement is to take four dosages of the herbal tea of the same prescription.

 

Date: Aug. 28, 2007                               Time: 9:00 a.m.

The patient felt that the strength of his left fingers increased. The muscular trembling was lessened. He had a little amount of phlegm. Doctor¡¯s requirement is to take three dosages of the herbal tea of the same prescription.

 

Date: Aug. 31, 2007                               Time: 9:00 a.m.

These days the patient has suffered from diarrhea with water-like bowel movement. He had no bellyache or any swelling of stomach. He had poor absorption and coughing. Doctor¡¯s requirement is to take five dosages of the herbal tea of the same prescription. 

 

Date: Sep. 1, 2007                               Time: 9:00 a.m.

The patient suffered from diarrhea with water-like bowel movement 3 to 4 times a day. He felt poor spirit with tired body during taking the self-prepared medicine for his diarrhea. He was given the injection 1000ml with 10% of potassium chloride 10ml and caloric agent. He took herbal tea orally to boost qi and fortify the spleen and help to digest. The doctor advised him not to eat the cold food or oily food.

 

Date: Sep. 4, 2007                               Time: 9:00 a.m.

The patient still suffered from diarrhea, 2 to 3 times a day. After using the agastache qi-righting Pills, his diarrhea was getting better. This morning, had only once bowel movement and his bowel movement returned to normal. The doctor still advised him to take the herbal tea. 

 

Date: Sep. 5, 2007                               Time: 9:00 a.m.

The patient suffered from diarrhea several days ago with poor intake and weakness body. He had history of diabetes, so could not give injection with some medicine containing any sugar or amino acid. He got an examination of his blood sugar, which showed 6.1. The doctor advised him to stop antidiabetic medicines, and he should take them again after he returned his function of diet and digestion of intestinal tract. The herbal tea is to fortify the spleen, transform the food, soften the liver and extinguish the wind.

 

Date: Sep. 6th 2007                               Time: 11:40 a.m.

The patient complained that he had suffered diarrhea again with 4 to 5 times bowel movement last night. He felt weak with low spirit, poor appetite and poor sleep. The herbal tea Poria and Ovate Atractylodes Powder was to prescribe for his diarrhea. The doctor gave him three dosages of the herbal tea, and One dosage a day and drink twice. The western medicine was the injection with 10% glucose 500ml + vitamin C 2.0 + 10% potassium chloride 10ml + amino acid 250 ml to supplement enough energy. Since the patient had the history of diabetes, he was give 8 ml insulin instead of 500 ml glucose, so as to prevent the patient¡¯ s blood sugar increasing. The patient was given the careful treatment and would continue to take the examination when necessary.

Date: Sep. 12th 2007                               Time: 9:00 a.m.

The patient had 3 times bowel movement yesterday morning since he had eaten eggs. After examination, the patient was considered to be with poor digestion. The doctor advised him not to take any eggs or oily food at this time. The patient¡¯s former herbal tea should add blast-fried ginger 7 g, aconite accessory tuber 12g, and mume fruit 20 g.  

 

Date: Sep. 13th 2007                               Time: 9:00 a.m.

The patient¡¯s diarrhea recovered by taking the medicine to warm and supplement the spleen, and he had only once bowel movement today. His appetite increased and his spirit was getting better. The herbal tea prescription is the same as the former.

 

Date: Sep. 16th 2007                               Time: 9:00 a.m.

The patient¡¯s bowel movement was normal, his appetite increased, and his spirit was getting better. His muscular trembling was lessened. His tongue was still numb, and he had difficulty in swallowing. His month was slightly dry. The herbal tea prescription is the same as the former.

 

Date: Sep. 19th 2007                               Time: 9:00 a.m.

The patient¡¯s bowel movement was normal, his appetite increased obviously and he could swallow food. His muscular trembling was lessened day by day. He was still weak and tired since he had suffered from diarrhea before. He had no dry month. Doctor¡¯s requirement is to take four dosages of the herbal tea of the same prescription as Sep. 16th.

 

Date: Sep. 23rd 2007                               Time: 9:00 a.m.

The patient¡¯s condition was normal. There were some slight pains on his lower limbs. Doctor¡¯s requirement is to take five dosages of the herbal tea of the same prescription.

 

Date: Sep. 25th 2007                               Time: 10:00 a.m.

After hospitalization in our hospital and the treatment of our herbal tea accompanied by acupuncture and massage and some exercise, the ALS patient¡¯s difficulties in swallowing and speaking, and his muscular trembling all achieved significant improvement. Today, he demanded to leave the hospital with 3-month herbal tea for home taking.

The main herbs such as white ginseng, astragalus root, salvia root, etc are contained in the 90-day herbal tea.

The main herbs such as white ginseng, astragalus root, ovate atractylodes root, etc are contained in the 5-day honey pills.

 

Date: Sep. 28th 2007                               Time: 9:00 a.m.

The patient had diarrhea last night again with twice loose bowel movement. He also felt some bellyache. The doctor prescribed him the herbal tea decocted with agastache, aconite accessory tuber, and mume fruit. This morning he still had diarrhea with some bellyache. His other condition was good without dry month. Doctor¡¯s requirement is to take two dosages of the herbal tea of the same prescription.

 

Date: Sep. 30th 2007                               Time: 9:00 a.m.

After hospitalization in our hospital and the treatment of our herbal tea accompanied by acupuncture and massage and some exercise, the ALS patient¡¯s difficulties in swallowing and speaking, and his muscular trembling all achieved significant improvement. His poor intake, weak and tired body also was improved obviously. Now he has no diarrhea, and the strength of his limbs increased a lot. He kept a good mood. He demanded to leave the hospital with three-month herbal tea and 5-day honey pills for home taking.

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