TCM China:  

The Academic Report About Our Hospital By Moni From Kosovo, ALS
 

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Brief Summary: Moni has suffered from four limbs amyotrophy progressively for 13 years, accompanied by inability to walk for three years. After about twenty-day treatment here, his condition has been improved a lot.

 

Records of Hospitalization

Name: Moni                                                                                                        Sex: Male

Age: 42                                                                                                               Profession:  Businessman

Nationality: Kosovo                                                                                           Marital status: Married

Onset Season: Summer                                                                                      Date of Admission: Mar.25th, 2007 

Complainer of history: The patient himself                                                          Date of Admission: Mar.25th, 2007 

Chief complaint: The patient has suffered from four limbs amyotrophy progressively 13 years accompanied by unable to walk three years.

Present illness: On March 1994, the patient began to have four limbs weakness without any obvious cause. He had not done any examination or treatment about it due to ignorance, it obviously progressively grew worse and his four limbs started to atrophy after half a year. He then took a MRI scan in a local hospital (not in detail). The accurate diagnosis for him is amyotrophic lateral sclerosis (ALS) by the MRI scan. The doctors in the hospital told him that there was no therapeutic schedule for his disease and he could not be cured. They gave the patient vitamin C and vitamin E to orally taken for trophic nerve. The patient¡¯s condition progressively grew worse. On February 2004, the patient began to unable to walk and needed to use wheelchair, but he did not do any treatment on it. He came to hospitalize in our Traditional Chinese Medicine (TCM) Department today. His spirit, appetite and sleep are bad since he has gotten this disease; his bowel movement and urination are normal.

Past history: He was quite health before. No history of typhoid, tuberculosis, diarrhea and hepatitis or other history of communicable disease. No history of traumatism or operation. No history of medicine or food allergy. No history of transfusion.  No history of preventive vaccination provided.

Personal history: He was born in Kosovo. No contact history of schistosomiasis. No addiction to alcohol or smoke. No addiction to special food. He is gentle and open minded.

Marital history: He married at 23 and has three sons. His wife and children are all healthy.

Family history: His parents are both healthy. No family history of special disease.

Physical examination

T: 36.6¡æ£¬P: 91bpm, R: 23bpm, BP: 180/123mmHg

He is mid-nourished and normally developed. His mind is clear, chronic face mirroring difficult condition and languor expression. He is in a positive position and cooperative in examination. His skin is moist. No jaundice in the sclera. No superficial lymph-node enlargement. Bilateral pupils are round and equal in size and sensitive to light. No thoracic deformity. Sound of breath is bilaterally normal on auscultation. No respiratory rales or pleural friction rubs. Heart border is normal. Heart beat 80bpm. Cardiac rhythm is regular. No pathological murmurs of heart on auscultation. Abdomen is flat and soft without tenderness or rebound tenderness. No percussion pain on renal region. Bowel sound is normal. No Spinal and pelvic deformity or tenderness. Four limbs will see in special examination. The development of the anus or pudendum is normal. He has physiological reflex, but the pathological features are not elicited out.

Special examination: Obvious bilateral atrophia on his supraspinous muscle and infraspinous muscle. His musculus biceps brachii and musculus triceps brachii are nearly disappeared due to atrophia on bilateral upper arms. The atrophia on his forearms obviously presents as flat paten and the muscles are basically disappeared. Both of his hands presents like the hand of apes. It is very hard for him to move his fingers. He can not carry things. The myodynamia of his lower limbs are grade two and myatonia. The diameters are 15cm measured on his left and right forearms; the diameters are 19cm on his left and right upper arms. His muscles are obviously atrophied. It is very difficult for him to move his lower limbs. The experiments of straighten-and-risen-up are 10 degree (+) on his left and right legs. The jerk reflex is weakened on his knee and his tendon reflex is basically disappeared. Karyotype (£­), babinski (£­). The myodynamia are grade II and myatonia on his lower limbs.

Accessory examination: It is vacant at the moment.

First diagnosis: TCM diagnosis: Wei-syndrome (flaccidity syndrome)

Symptom diagnosis: Weakness of the liver and spleen; phlegm-heat brewing internally.

WM diagnosis: Amyotrophic lateral sclerosis (ALS).

Dr. Zhang Xiukui/ Dr. Dai Lei

 

 

First Medical Record

Moni, a 42-year-old male, has suffered from four limbs amyotrophy progressively 13 years accompanied by unable to walk three years. He was met by our workers in Zhijiang Airport and arrived in Huaihua Red Cross Hospital at 18: 30, March 24th, 2007.

Essentials for diagnosis:

1. The patient has suffered from four limbs amyotrophy progressively 13 years accompanied by unable to walk three years.

2. On March 1994, the patient began to have four limbs weakness without any obvious cause. He had not done any examination or treatment about it due to ignorance, it obviously progressively grew worse and his four limbs started to atrophy after half a year. He then took a MRI scan in a local hospital (not in detail). The accurate diagnosis for him is amyotrophic lateral sclerosis (ALS) by the MRI scan. The doctors in the hospital told him that there was no therapeutic schedule for his disease and he could not be cured. They gave the patient vitamin C and vitamin E to orally taken for trophic nerve. The patient¡¯s condition progressively grew worse. On February 2004, the patient began to unable to walk and needed to use wheelchair, but he did not do any treatment on it. He came to hospitalize in our Traditional Chinese Medicine (TCM) Department today. His spirit, appetite and sleep are bad since he has gotten this disease; his bowel movement and urination are normal.

3. T: 36.6¡æ£¬P: 91bpm, R: 23bpm, BP: 180/123mmHg

4. He is mid-nourished and normally developed. His mind is clear, chronic face mirroring difficult condition and languor expression. He is in a positive position and cooperative in examination.

5. He has obvious bilateral atrophia on his supraspinous muscle and infraspinous muscle. His musculus biceps brachii and musculus triceps brachii are nearly disappeared due to atrophia on bilateral upper arms. The atrophia on his forearms obviously presents as a ¡°flat paten¡± and the muscles are basically disappeared. Both of his hands presents as the hands of apes. It is very hard for him to move his fingers. He can not carry things. His myodynamia is grade II and myatonia. The diameters are 15cm measured on his left and right forearms; the diameters are 19cm on his left and right upper arms. His muscles are obviously atrophied at this part. It is very difficult for him to move his lower limbs. The experiments of straighten-and-risen-up are 10 degree (+) on his left and right legs. The jerk reflex is weakened on his knee and his tendon reflex is basically disappeared. Karyotype (£­), babinski (£­). The myodynamia are grade II and myatonia on his lower limbs. He got polypnea sometimes, especially during the evening.

6. No thoracic deformity. Chest percussion notes resonance. Sound of breath is bilaterally clear on auscultation. No pleural friction rubs.

7. Accessory examination: Not provided yet.

Diagnostic basis

TCM: The patient has suffered from four limbs amyotrophy progressively 13 years accompanied by unable to walk three years. His four limbs are limp wilting; his body sinews and vessels are atonicity. He has obvious bilateral atrophia on his supraspinous muscle and infraspinous muscle on his limbs. It is very hard for him to move or to exhale and inhale, especially during the night time. The symptoms all above are pertained to Wei-syndrome.

Western medicine: The patient has suffered from four limbs amyotrophy progressively 13 years accompanied by unable to walk three years. He has obvious bilateral atrophia on his supraspinous muscle and infraspinous muscle. His musculus biceps brachii and musculus triceps brachii are nearly disappeared due to atrophia on bilateral upper arms. The atrophia on his forearms obviously presents as a ¡°flat paten¡± and the muscles are basically disappeared. Both of his hands presents as the hands of apes. It is very hard for him to move his fingers. He can not carry things. His myodynamia is grade II and myatonia. The diameters are 15cm measured on his left and right forearms; the diameters are 19cm on his left and right upper arms. His muscles are obviously atrophied at this part. It is very difficult for him to move his lower limbs. The experiments of straighten-and-risen-up are 10 degree (+) on his left and right legs. The jerk reflex is weakened on his knee and his tendon reflex is basically disappeared. Karyotype (£­), babinski (£­). The myodynamia are grade II and myatonia on his lower limbs. He got polypnea sometimes, especially mush worse during the night times. On September 1994, he took MRI scan in a local hospital (not in detail) and got the accurate diagnosis which was amyotrophic lateral sclerosis (ALS).

Diagnostic differentiation

TCM: The patient¡¯s Wei-syndrome should be differentiated from Bi-syndrome. Although they both fall into the category of limb disease, they are different in pathogeny, pathogenesis and clinical manifestations. Wei-syndrome is characterized as limp, weak and emaciated limbs with shriveled muscles. A patient suffering from Wei-syndrome may even become unable to hold an object or to stand without support. Besides, the patient¡¯s lower limbs are more often affected, though he or she usually has no joint pain. On the contrary, Bi-syndrome is generally characterized as aching pain, fixed heaviness and inflexibility of sinews and bones, muscles and joints, with occasional numbness or swelling, though, no paralytic manifestations. The pathogenesis of Wei-syndrome is that the essence and blood in five-fu organs is insufficient to travel through the whole body leading to malnourish of the meridians and collaterals; while that of Bi-syndrome is that the obstruction of meridians and collaterals by pathogenic qi blocks the circulation of qi and blood. So it is not hard to differentiate Wei-syndrome from Bi-syndrome in clinical manifestations.

WM: The patient¡¯s ALS (amyotrophic lateral sclerosis) should be differentiated from myasthenia gravis pseudoparalytica which occurs to any aged people, mostly between 10 to 35 years old and more female suffered from it than male do, and the proportion is about 2-4.5:1. The typical characteristic is that the using skeletal muscles are very easily fatigability, but it would be more or less better after some rest; fluctuate of patients¡¯ condition, and it is much worse in the evening time, many illnesses onset secretly. Usually it onset from one group of muscle to other groups, and involved in cranial innervations first be put into trouble which is mostly common to see. It should be differentiated that different aged myasthenia patients, their clinical manifestation or course of disease are differenced from each other. 

First diagnosis: TCM diagnosis: Wei-syndrome (flaccidity syndrome)

Symptom diagnosis: Weakness of the liver and spleen; phlegm-heat brewing internally.

WM diagnosis: Amyotrophic lateral sclerosis (ALS)

Plan of treatment and care

1. On routine care of traditional Chinese internal medicine

2. On grade II care

3. Nurse

4. High protein diet

5. Herbal tea: boost qi and fortify the spleen, enrich the liver and kidney, clear heat and transform phlegm. Prescription: belamcanda (Shegan), astragalus (Huangqi), moutan (Danpi), etc. Four days, one dosage a day and drink by twice.

6. Massage and acupuncture: once a day

7. Some proper functional training.

8. Have more medical examinations if necessary.

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Date: 27th of March, 2007                           Time: 2 p.m.

The patient complains to Dr. Zhang that his appetite is better and can take in more food. He says that there is no throat pain, less expectoration. He has a good sleep and his spirit is good. His bowel movement and urination are normal. He has general muscular atrophy, especially on his forearms. His wrist joints and figure joints neither can not do flexion and extension movement nor hold in fists. He can not carry chopsticks nor hold subjects. He needs some one to feed him. His limbs are weak. He can not rise up his feet nor walk by himself. His ankle joints and digital joints can not do flexion and extension movement. His pharyngeal portion gets inflammation and swollen. Slimy and pale yellow coating tongue fur, red-purple tongue, slippery and forceless pulse. The doctor gives him herbal medicine to boost qi and fortify the spleen, clear heat and transform phlegm, enrich the liver and kidney. The prescription is belamcanda (Shegan), astragalus (Huangqi), moutan (Danpi), etc. One dosage a day and drink by twice, four days.      

Dr. Zhang Xiukui

 

Date: 31st of March, 2007                           Time: 3 p.m.

The patient complains to Dr. Zhang that his appetite is basically normal. He says he has polypnea and sense of obstruction in his throat. He feels like phlegm inside, but he does not have expectoration. Slight-slimy and pale yellow coating tongue fur, red-purple tongue and slippery pulse. The doctor tells the patient to take more nutrition food, increase exercise and functional training. The doctor gives him herbal medicine to fortify the spleen and transform phlegm, boost qi and quicken the blood, enrich the liver and kidney. The prescription is zhebei (zhejiang fritillaria), danpi (cortex moutan), chenpi (dried orange peel), etc. One dosage a day and drink by twice, three days.

Dr. Zhang Xiukui

 

Date: 3rd of April, 2007                           Time: 9 a.m.

Generally the patient¡¯s condition is good. Continue given him the former prescription, but take shegan (belam canda) out and add 20g of maohuang (lanaurin).One dosage a day and drink by twice, three days. Continue combining supply a bottle of 10% klinitamin and energy. Keep observing the patient¡¯s condition. 

Dr. Zhang Xiukui

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Date: 6th of April, 2007                           Time: 9 a.m.

The patient says his apatite is very good today. He feels much better about the block sense of phlegm in his throat. His sleep is normal. He feels his body condition is becomes better and better day after day. He very seldom had polypnea and short breathe last night. It last very short and then disappeared. The back side of this throat is a little red and slight swollen. Slimy and pale yellow coating tongue fur, and slippery pulse. The prescription for him is maohuang (lanaurin), zhebei (zhejiang fritillaria), astragalus (Huangqi), etc. One dosage a day and drink by twice, four days.     

Dr. Zhang Xiukui

 

Date: 10th of April, 2007                           Time: 10 a.m.

The patient complains that he had slight chest tightness, polypnea and feels thirsty last night. He does not have expectoration. His lower limbs are cold, but heat in the center feet. His sleep is good and his diet is normal. The doctor found the back of his throat is slightly red and swollen. His bilateral upper limbs, wrist joints and figure joints all can not do flexion and extension movement. His ankle joints and digital joints also can not do flexion and extension movement. Besides given him herbal tea, acupuncture and massage, the doctor also gives him medicine of warm the channels and free the network vessels to marinate and external wash once a day in order to observe. Since the patient admitted in the hospital, his weight increased 3 kg in half a month. The prescription for orally taken is Baishen (white ginseng), maohuang (lanaurin), danpi (cortex moutan), etc. One dosage a day and drink by twice, four days. The prescription for external using is aiye (Artemisia leaf), yimucao (leonurus), kuqin (scutellaria), etc. Decoct the medicine in water for external using in the afflicted part, six days.   

Dr. Zhang Xiukui

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Date: 14th of April, 2007                           Time: 10 a.m.

The patient presents a good spirit. His diet and sleep are normal. He very seldom has chest tightness or the sense of obstruction in his throat. The doctor finds his throat is slight red and swollen. The doctor considers it is chronic pharyngitis. Slimy and pale yellow coating tongue fur, fine and weak pulse. The prescription for him is maohuang (lanaurin), bairenshen (white ginseng), astragalus (Huangqi), etc. One dosage a day and drink by twice, four days.     

Dr. Zhang Xiukui

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Date: 19th of April, 2007                           Time: 9 a.m.

The patient and his wife are going to Hong Kong to renew the visas, so the doctors temporarily stop all the treatment. 

Dr. Zhang Xiukui

 

Date: 20th of April, 2007                           Time: 10 a.m.

The patient and his wife have to come back to their country to get new visas, so the treatment is temporarily stopped. 

Dr. Zhang Xiukui

 

Date: 20th of April, 2007                           Time: 3 p.m.

Because the patient and his wife did not get the new visa, they have to end the treatment and admit out the hospital.

Dr. Zhang Xiukui

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